Tamoxifen is a nonsteroidal SERM of the triphenylethylene family and was structurally derived from diethylstilbestrol -like estrogens and antiestrogens such as chlorotrianisene and ethamoxytriphetol. [103][104][105][106] Initially, clomifene was synthesized, and tamoxifen was developed subsequently. [103][105][106] Tamoxifen is closely related. Tamoxifen (Nolvadex), a hormone therapy drug, is used to treat hormone-receptor positive breast cancers. Tamoxifen is an antiestrogen drug used in the treatment of breast cancer. It blocks the activity of estrogen, helping to stop the growth of some tumors. Tamoxifen (ta-MOX-i-fen) is a drug that is used to treat many types of cancers. Some cancers are hormone sensitive (estrogen or progesterone receptor positive) and their growth can be affected by blocking the effect of the hormone estrogen. Tamoxifen is used to treat some types of breast cancer in men and women. Tamoxifen is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer). Tamoxifen and raloxifene have been shown to reduce the risk of breast cancer for some women. Learn more about these medications and their possible side effects. Tamoxifen is used to treat breast cancer that has spread to other parts of the body in men and women. It is used to treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Tamoxifen (brand names: Nolvadex, Soltamox) is a medicine that blocks the effects of the hormone estrogen (called a selective estrogen receptor modulator, or SERM). Tamoxifen is a first choice among doctors for treating women who have not yet gone through menopause. Overview: Tamoxifen is commonly used to treat certain types of breast cancer. It is also used to lower your risk of invasive breast cancer and keep some breast cancers from coming back. It blocks. Tamoxifen is a prescription medicine that is used to treat breast cancer in men and women. It is in a class known as a selective estrogen receptor modulator (SERM) and is used to treat hormone receptor-positive breast cancer.